Severe α1-antitrypsin deficiency and pregnancy
نویسندگان
چکیده
منابع مشابه
Severe a 1 - antitrypsin deficiency and pregnancy
This case study describes a successful pregnancy in a 27-yr-old patient with severe emphysema, secondary to a1-antitrypsin deficiency, genotype PiZZ. Despite significant respiratory compromise, more severe than previously reported, no complications ensued. Maternal pulmonary function did not deteriorate significantly until the 32nd week of pregnancy, with an elective Caesarean section being per...
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www.thelancet.com Published online May 28, 2015 http://dx.doi.org/10.1016/S0140-6736(15)60036-8 1 α1 antitrypsin is a serine antiprotease secreted by the liver. Its main function is inhibition of neutrophil elastase, a non-specifi c protease released by activated or dying neutrophils. In individuals with healthy concentrations of α1 antitrypsin, the fragile alveolar structures of the lung paren...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 1999
ISSN: 0903-1936,1399-3003
DOI: 10.1034/j.1399-3003.1999.13f40.x